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Antimicrobial mechanism of pore-forming protegrin peptides: 100 pores to kill E. coli
Antimicrobial peptides (AMPs), important effector molecules of the innate immune system, also provide templates for designing novel antibiotics. Protegrin, an especially potent AMP found in porcine leukocytes, was recently shown to form octameric transmembrane pores. We have employed a combination o...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825693/ https://ncbi.nlm.nih.gov/pubmed/19931583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2009.11.010 |
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