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Stress-induced Switch in Numb Isoforms Enhances Notch-dependent Expression of Subtype-specific Transient Receptor Potential Channel

The Notch signaling pathway plays an essential role in the regulation of cell specification by controlling differentiation, proliferation, and apoptosis. Numb is an intrinsic regulator of the Notch pathway and exists in four alternative splice variants that differ in the length of their phosphotyros...

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Detalhes bibliográficos
Main Authors: Kyriazis, George A., Belal, Cherine, Madan, Meenu, Taylor, David G., Wang, Jang, Wei, Zelan, Pattisapu, Jogi V., Chan, Sic L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825475/
https://ncbi.nlm.nih.gov/pubmed/20038578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074690
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