Heart-specific Deletion of CnB1 Reveals Multiple Mechanisms Whereby Calcineurin Regulates Cardiac Growth and Function

Calcineurin is a protein phosphatase that is uniquely regulated by sustained increases in intracellular Ca(2+) following signal transduction events. Calcineurin controls cellular proliferation, differentiation, apoptosis, and inducible gene expression following stress and neuroendocrine stimulation....

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Main Authors: Maillet, Marjorie, Davis, Jennifer, Auger-Messier, Mannix, York, Allen, Osinska, Hanna, Piquereau, Jérôme, Lorenz, John N., Robbins, Jeffrey, Ventura-Clapier, Renée, Molkentin, Jeffery D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825466/
https://ncbi.nlm.nih.gov/pubmed/20037164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056143
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