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The Human Carnitine Transporter SLC22A16 Mediates High Affinity Uptake of the Anticancer Polyamine Analogue Bleomycin-A5

Bleomycin is used in combination with other antineoplastic agents to effectively treat lymphomas, testicular carcinomas, and squamous cell carcinomas of the cervix, head, and neck. However, resistance to bleomycin remains a persistent limitation in exploiting the full therapeutic benefit of the drug...

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Detalhes bibliográficos
Main Authors: Aouida, Mustapha, Poulin, Richard, Ramotar, Dindial
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825423/
https://ncbi.nlm.nih.gov/pubmed/20037140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.046151
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