Molecular Characterization of the Interaction of Staphylococcal Microbial Surface Components Recognizing Adhesive Matrix Molecules (MSCRAMM) ClfA and Fbl with Fibrinogen

The ligand-binding domain of Fbl (the fibrinogen binding protein from Staphylococcus lugdunensis) shares 60% sequence identity with ClfA (clumping factor A) of Staphylococcus aureus. Recombinant Fbl corresponding to the minimum fibrinogen-binding region (subdomains N2N3) was compared with ClfA for b...

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Main Authors: Geoghegan, Joan A., Ganesh, Vannakambadi K., Smeds, Emanuel, Liang, Xiaowen, Höök, Magnus, Foster, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825416/
https://ncbi.nlm.nih.gov/pubmed/20007717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.062208
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