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Voltage-dependent Anion Channel 1-based Peptides Interact with Bcl-2 to Prevent Antiapoptotic Activity

The antiapoptotic proteins of the Bcl-2 family are expressed at high levels in many types of cancer. However, the mechanism by which Bcl-2 family proteins regulate apoptosis is not fully understood. Here, we demonstrate the interaction of Bcl-2 with the outer mitochondrial membrane protein, voltage-...

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Autors principals: Arbel, Nir, Shoshan-Barmatz, Varda
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825399/
https://ncbi.nlm.nih.gov/pubmed/20037155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.082990
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