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Oligomerization of the Mitochondrial Protein Voltage-Dependent Anion Channel Is Coupled to the Induction of Apoptosis

Accumulating evidence implicates that the voltage-dependent anion channel (VDAC) functions in mitochondrion-mediated apoptosis and as a critical player in the release of apoptogenic proteins, such as cytochrome c, triggering caspase activation and apoptosis. The mechanisms regulating cytochrome c re...

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Detalhes bibliográficos
Main Authors: Keinan, Nurit, Tyomkin, Dalia, Shoshan-Barmatz, Varda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004265/
https://ncbi.nlm.nih.gov/pubmed/20937774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00165-10
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