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Modulatory effects of neuropsychopharmaca on intracellular pH of hippocampal neurones in vitro

BACKGROUND AND PURPOSE: The intracellular pH (pHi) of neurones is tightly regulated by, for example, membrane-bound acid-exchangers and loaders. Nevertheless, excessive bioelectric activity lowers steady-state pHi. In turn, even a moderate acidification can inhibit neuronal activity, a process belie...

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Détails bibliographiques
Auteurs principaux: Bonnet, Udo, Bingmann, Dieter, Wiltfang, Jens, Scherbaum, Norbert, Wiemann, Martin
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825368/
https://ncbi.nlm.nih.gov/pubmed/20015293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00540.x
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