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Levetiracetam inhibits Na(+)-dependent Cl(−)/HCO(3)(−) exchange of adult hippocampal CA3 neurons from guinea-pigs
1. The novel anticonvulsant levetiracetam (LEV) was tested for effects on bioelectric activity and intracellular pH (pHi) regulation of hippocampal CA3 neurons from adult guinea-pigs. 2. In 4-aminopyridine-treated slices, LEV (10–100 μM) reduced the frequency of action potentials and epileptiform bu...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1575181/ https://ncbi.nlm.nih.gov/pubmed/15249428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705836 |
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