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BDNF-Hypersecreting Human Mesenchymal Stem Cells Promote Functional Recovery, Axonal Sprouting, and Protection of Corticospinal Neurons after Spinal Cord Injury

Transplantation of mesenchymal stem cells (MSCs) derived from bone marrow has been shown to improve functional outcome in spinal cord injury (SCI). We transplanted MSCs derived from human bone marrow (hMSCs) to study their potential therapeutic effect in SCI in the rat. In addition to hMSCs, we used...

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Autori principali: Sasaki, Masanori, Radtke, Christine, Tan, Andrew M., Zhao, Peng, Hamada, Hirofumi, Houkin, Kiyohiro, Honmou, Osamu, Kocsis, Jeffery D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825276/
https://ncbi.nlm.nih.gov/pubmed/19940189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2769-09.2009
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