BDNF-Hypersecreting Human Mesenchymal Stem Cells Promote Functional Recovery, Axonal Sprouting, and Protection of Corticospinal Neurons after Spinal Cord Injury

Transplantation of mesenchymal stem cells (MSCs) derived from bone marrow has been shown to improve functional outcome in spinal cord injury (SCI). We transplanted MSCs derived from human bone marrow (hMSCs) to study their potential therapeutic effect in SCI in the rat. In addition to hMSCs, we used...

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Main Authors: Sasaki, Masanori, Radtke, Christine, Tan, Andrew M., Zhao, Peng, Hamada, Hirofumi, Houkin, Kiyohiro, Honmou, Osamu, Kocsis, Jeffery D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825276/
https://ncbi.nlm.nih.gov/pubmed/19940189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2769-09.2009
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