Addition of a foreign oligopeptide to the major capsid protein of poliovirus.
Insertion mutants of type 3 poliovirus (Sabin strain) were constructed that encode additional amino acid sequences at the level of residue 100 of the capsid polypeptide VP1 within the neutralization site 1, corresponding to a loop on the capsid surface. The addition of a tri- or hexapeptide did not...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1988
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282521/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2460875/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.22.8668 |
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