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Addition of a foreign oligopeptide to the major capsid protein of poliovirus.

Insertion mutants of type 3 poliovirus (Sabin strain) were constructed that encode additional amino acid sequences at the level of residue 100 of the capsid polypeptide VP1 within the neutralization site 1, corresponding to a loop on the capsid surface. The addition of a tri- or hexapeptide did not...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Colbère-Garapin, F, Christodoulou, C, Crainic, R, Garapin, A C, Candrea, A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282521/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2460875/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.22.8668
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