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CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.
Evidence is presented that the leukocyte common antigen CD45 can regulate both signal transduction by lymphocyte receptor molecules and T- and B-cell proliferation in a manner dependent on specific interactions between these receptors on the cell surface. Formation of homoaggregates of CD3, CD2, or...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1988
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282512/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2973067/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.22.8628 |
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