Partial suppression of anchorage-independent growth and tumorigenicity in immunodeficient mice by transfection of the H-2 class I gene H-2Ld into a human colon cancer cell line (HCT).

Many human tumors, particularly those of epithelial origin, appear to express greatly reduced levels of major histocompatibility complex class I antigens on their surface. It has been previously reported that the class I gene H-2Ld, introduced into adenovirus type 12-transformed mouse cells, induces...

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Hauptverfasser: Gattoni-Celli, S, Willett, C G, Rhoads, D B, Simon, B, Strauss, R M, Kirsch, K, Isselbacher, K J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC282495/
https://ncbi.nlm.nih.gov/pubmed/3186742
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