Partial suppression of anchorage-independent growth and tumorigenicity in immunodeficient mice by transfection of the H-2 class I gene H-2Ld into a human colon cancer cell line (HCT).

Many human tumors, particularly those of epithelial origin, appear to express greatly reduced levels of major histocompatibility complex class I antigens on their surface. It has been previously reported that the class I gene H-2Ld, introduced into adenovirus type 12-transformed mouse cells, induces...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gattoni-Celli, S, Willett, C G, Rhoads, D B, Simon, B, Strauss, R M, Kirsch, K, Isselbacher, K J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282495/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3186742/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.22.8543
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