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CONTROL OF α4β7 INTEGRIN EXPRESSION AND CD4 T CELL HOMING BY THE β1 INTEGRIN SUBUNIT

The α4β7 integrin promotes homing of T cells to intestinal sites. The α4 integrin subunit that pairs with β7 integrin can also pair with β1 integrin. Here, we show that the preferential pairing of β1 integrin with α4 integrin regulates the expression of α4β7 on T cells. In the absence of β1 integrin...

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Main Authors: DeNucci, Christopher C., Pagan, Antonio J., Mitchell, Jason S., Shimizu, Yoji
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824783/
https://ncbi.nlm.nih.gov/pubmed/20118278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902407
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