Optineurin Negatively Regulates the Induction of IFNβ in Response to RNA Virus Infection

The innate immune response provides a critical defense against microbial infections, including viruses. These are recognised by pattern recognition receptors including Toll-like receptors (TLRs) and RIG-I like helicases (RLHs). Detection of virus triggers signalling cascades that induce transcriptio...

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Detalhes bibliográficos
Main Authors: Mankouri, Jamel, Fragkoudis, Rennos, Richards, Kathryn H., Wetherill, Laura F., Harris, Mark, Kohl, Alain, Elliott, Richard M., Macdonald, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824764/
https://ncbi.nlm.nih.gov/pubmed/20174559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000778
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