Numerical Modelling Of The V-J Combinations Of The T Cell Receptor TRA/TRD Locus

T-Cell antigen Receptor (TR) repertoire is generated through rearrangements of V and J genes encoding α and β chains. The quantification and frequency for every V-J combination during ontogeny and development of the immune system remain to be precisely established. We have addressed this issue by bu...

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Détails bibliographiques
Auteurs principaux: Thuderoz, Florence, Simonet, Maria-Ana, Hansen, Olivier, Pasqual, Nicolas, Dariz, Aurélie, Baum, Thierry Pascal, Hierle, Vivien, Demongeot, Jacques, Marche, Patrice Noël, Jouvin-Marche, Evelyne
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824756/
https://ncbi.nlm.nih.gov/pubmed/20174554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000682
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