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Sheep (Ovis aries) T cell receptor alpha (TRA) and delta (TRD) genes and genomic organization of the TRA/TRD locus

BACKGROUND: In mammals, T cells develop along two discrete pathways characterized by expression of either the αβ or the γδ T cell receptors. Human and mouse display a low peripheral blood γδ T cell percentage ("γδ low species") while sheep, bovine and pig accounts for a high proportion of...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Piccinni, Barbara, Massari, Serafina, Caputi Jambrenghi, Anna, Giannico, Francesco, Lefranc, Marie-Paule, Ciccarese, Salvatrice, Antonacci, Rachele
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574546/
https://ncbi.nlm.nih.gov/pubmed/26383271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1790-z
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