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Identifying the Rules of Engagement Enabling Leukocyte Rolling, Activation, and Adhesion

The LFA-1 integrin plays a pivotal role in sustained leukocyte adhesion to the endothelial surface, which is a precondition for leukocyte recruitment into inflammation sites. Strong correlative evidence implicates LFA-1 clustering as being essential for sustained adhesion, and it may also facilitate...

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Detalhes bibliográficos
Main Authors: Tang, Jonathan, Hunt, C. Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824748/
https://ncbi.nlm.nih.gov/pubmed/20174606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000681
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