Stabilization of Endothelial Receptor Arrays by a Polarized Spectrin Cytoskeleton Facilitates Rolling and Adhesion of Leukocytes

Multivalent complexes of endothelial adhesion receptors (e.g., selectins) engage leukocytes to orchestrate their migration to inflamed tissues. Proper anchorage and sufficient density (clustering) of endothelial receptors are required for efficient leukocyte capture and rolling. We demonstrate that...

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Publicado en:Cell Rep
Main Authors: Mylvaganam, Sivakami, Riedl, Magdalena, Vega, Anthony, Collins, Richard F., Jaqaman, Khuloud, Grinstein, Sergio, Freeman, Spencer A.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548125/
https://ncbi.nlm.nih.gov/pubmed/32579925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107798
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