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Stabilization of Endothelial Receptor Arrays by a Polarized Spectrin Cytoskeleton Facilitates Rolling and Adhesion of Leukocytes

Multivalent complexes of endothelial adhesion receptors (e.g., selectins) engage leukocytes to orchestrate their migration to inflamed tissues. Proper anchorage and sufficient density (clustering) of endothelial receptors are required for efficient leukocyte capture and rolling. We demonstrate that...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Mylvaganam, Sivakami, Riedl, Magdalena, Vega, Anthony, Collins, Richard F., Jaqaman, Khuloud, Grinstein, Sergio, Freeman, Spencer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548125/
https://ncbi.nlm.nih.gov/pubmed/32579925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107798
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