Stabilization of Endothelial Receptor Arrays by a Polarized Spectrin Cytoskeleton Facilitates Rolling and Adhesion of Leukocytes

Multivalent complexes of endothelial adhesion receptors (e.g., selectins) engage leukocytes to orchestrate their migration to inflamed tissues. Proper anchorage and sufficient density (clustering) of endothelial receptors are required for efficient leukocyte capture and rolling. We demonstrate that...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Mylvaganam, Sivakami, Riedl, Magdalena, Vega, Anthony, Collins, Richard F., Jaqaman, Khuloud, Grinstein, Sergio, Freeman, Spencer A.
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548125/
https://ncbi.nlm.nih.gov/pubmed/32579925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107798
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