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Point mutants of Moloney murine leukemia virus that fail to package viral RNA: evidence for specific RNA recognition by a "zinc finger-like" protein sequence.

All retroviruses encode a nucleic acid-binding or nucleocapsid protein that is believed to be associated with RNA in the virion. Further, all retroviral nucleocapsid proteins contain either one or two copies of the sequence Cys-Xaa2-Cys-Xaa4-His-Xaa4-Cys. The conservation of this sequence suggested...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Gorelick, R J, Henderson, L E, Hanser, J P, Rein, A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282469/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3141927/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.22.8420
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