Point mutants of Moloney murine leukemia virus that fail to package viral RNA: evidence for specific RNA recognition by a "zinc finger-like" protein sequence.

All retroviruses encode a nucleic acid-binding or nucleocapsid protein that is believed to be associated with RNA in the virion. Further, all retroviral nucleocapsid proteins contain either one or two copies of the sequence Cys-Xaa2-Cys-Xaa4-His-Xaa4-Cys. The conservation of this sequence suggested...

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Main Authors: Gorelick, R J, Henderson, L E, Hanser, J P, Rein, A
格式: Artigo
語言:Inglês
出版: 1988
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC282469/
https://ncbi.nlm.nih.gov/pubmed/3141927
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