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A signal peptide encoded within the precore region of hepatitis B virus directs the secretion of a heterogeneous population of e antigens in Xenopus oocytes.

Using synthetic hepatitis B virus (HBV) mRNAs, we have shown that expression of HBV core-antigen gene sequences in Xenopus oocytes leads to the stable accumulation of 21-kDa cytoplasmic core protein (P21). In contrast, expression of precore plus core sequences leads mainly to the secretion of a hete...

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Библиографические подробности
Главные авторы: Standring, D N, Ou, J H, Masiarz, F R, Rutter, W J
Формат: Artigo
Язык:Inglês
Опубликовано: 1988
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC282466/
https://ncbi.nlm.nih.gov/pubmed/3186731
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