Cargando...

The CDK4-pRB-E2F1 pathway controls insulin secretion

CDK4-pRB-E2F1 cell cycle regulators are robustly expressed in non-proliferating β-cells, suggesting that besides the control of β-cell number the CDK4-pRB-E2F1 pathway has a role in β-cell function. We show here that E2F1 directly regulates the expression of Kir6.2, which is a key component of the K...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Annicotte, Jean-Sébastien, Blanchet, Emilie, Chavey, Carine, Iankova, Irena, Costes, Safia, Assou, Said, Teyssier, Jacques, Dalle, Stéphane, Sardet, Claude, Fajas, Lluis
Formato: Artigo
Lenguaje:Inglês
Publicado: Macmillan Magazines Ltd. 2009
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824657/
https://ncbi.nlm.nih.gov/pubmed/19597485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1915
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!