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Expression of diphtheria toxin fragment A and hormone-toxin fusion proteins in toxin-resistant yeast mutants.

Mutants of the eukaryote Saccharomyces cerevisiae, previously selected for resistance to diphtheria toxin, were investigated for their suitability as hosts for the expression of tox-related proteins. The structural gene for the toxin, encoding the fragment A catalytic domain, was modified for effici...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Perentesis, J P, Genbauffe, F S, Veldman, S A, Galeotti, C L, Livingston, D M, Bodley, J W, Murphy, J R
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1988
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282462/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2847158/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.22.8386
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