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Transgenic Expression of VEGF in Intestinal Epithelium Drives Mesenchymal Cell Interactions and Epithelial Neoplasia

BACKGROUND & AIMS: Vascular endothelial growth factor (VEGF) is expressed robustly in human colon neoplasia and is a major new ‘rational’ target of therapy for cancers of the colon and other organs. Nonetheless, the mechanism(s) of action of VEGF-targeted therapies and the biological roles of VE...

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Detalhes bibliográficos
Main Authors: Boquoi, Amelie, Jover, Rodrigo, Chen, Tina, Pennings, Marieke, Enders, Greg
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824597/
https://ncbi.nlm.nih.gov/pubmed/19056388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.10.028
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