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GroEL dependency affects codon usage—support for a critical role of misfolding in gene evolution
It has recently been suggested that the use of optimal codons limits mistranslation-induced protein misfolding, yet evidence for this remains largely circumstantial. In contrast, molecular chaperones have long been recognized to play crucial roles in misfolding prevention and remedy. We propose that...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824523/ https://ncbi.nlm.nih.gov/pubmed/20087338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.94 |
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