Assembly of a β(2)-adrenergic receptor—GluR1 signalling complex for localized cAMP signalling

Central noradrenergic signalling mediates arousal and facilitates learning through unknown molecular mechanisms. Here, we show that the β(2)-adrenergic receptor (β(2)AR), the trimeric G(s) protein, adenylyl cyclase, and PKA form a signalling complex with the AMPA-type glutamate receptor subunit GluR...

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Main Authors: Joiner, Mei-ling A, Lisé, Marie-France, Yuen, Eunice Y, Kam, Angel Y F, Zhang, Mingxu, Hall, Duane D, Malik, Zulfiqar A, Qian, Hai, Chen, Yucui, Ulrich, Jason D, Burette, Alain C, Weinberg, Richard J, Law, Ping-Yee, El-Husseini, Alaa, Yan, Zhen, Hell, Johannes W
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824466/
https://ncbi.nlm.nih.gov/pubmed/19942860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.344
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