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JNK1 Inhibits GluR1 Expression and GluR1-Mediated Calcium Influx through Phosphorylation and Stabilization of Hes-1

The GluR1 subunit of the AMPA receptor plays an important role in excitatory synaptic transmission and synaptic plasticity in the brain, but the regulation mechanism for GluR1 expression is largely unknown. Hairy and enhancer of split 1 (Hes-1) is a mammalian transcription repressor that regulates n...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Lin, Cheng H., Lee, Eminy H. Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703358/
https://ncbi.nlm.nih.gov/pubmed/22302822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3380-11.2012
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