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Progression of dopaminergic dysfunction in a LRRK2 kindred: A multitracer PET study

OBJECTIVE: Little is known about the progression of dopaminergic dysfunction in LRRK2-associated Parkinson disease (PD). We sought to characterize the neurochemical progression with multitracer PET in asymptomatic members of parkinsonian kindred (family D, Western Nebraska) carrying LRRK2 (R1441C) m...

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Detalhes bibliográficos
Main Authors: Nandhagopal, R, Mak, E, Schulzer, M, McKenzie, J, McCormick, S, Sossi, V, Ruth, T J., Strongosky, A, Farrer, M J., Wszolek, Z K., Stoessl, A J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Academy of Neurology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824449/
https://ncbi.nlm.nih.gov/pubmed/19029519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/01.wnl.0000335973.66333.58
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