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Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells

Invariant natural killer T cells (iNKT cells) respond to CD1d-presented glycolipids from Borrelia burgdorferi, the causative agent of Lyme disease. Although mouse and human iNKT cells respond to different antigens based on subtle differences in their fatty acids, the mechanism by which fatty acid st...

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Hlavní autoři: Wang, Jing, Li, Yali, Kinjo, Yuki, Mac, Thien-Thi, Gibson, Darren, Painter, Gavin F., Kronenberg, Mitchell, Zajonc, Dirk M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824385/
https://ncbi.nlm.nih.gov/pubmed/20080535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909479107
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