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Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells

Invariant natural killer T cells (iNKT cells) respond to CD1d-presented glycolipids from Borrelia burgdorferi, the causative agent of Lyme disease. Although mouse and human iNKT cells respond to different antigens based on subtle differences in their fatty acids, the mechanism by which fatty acid st...

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Main Authors: Wang, Jing, Li, Yali, Kinjo, Yuki, Mac, Thien-Thi, Gibson, Darren, Painter, Gavin F., Kronenberg, Mitchell, Zajonc, Dirk M.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824385/
https://ncbi.nlm.nih.gov/pubmed/20080535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909479107
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