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Platform for in situ real-time measurement of protein-induced conformational changes of DNA
A platform for in situ and real-time measurement of protein-induced conformational changes in dsDNA is presented. We combine electrical orientation of surface-bound dsDNA probes with an optical technique to measure the kinetics of DNA conformational changes. The sequence-specific Escherichia coli in...
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Auteurs principaux: | , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
National Academy of Sciences
2010
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824355/ https://ncbi.nlm.nih.gov/pubmed/20080702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912182107 |
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