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Platform for in situ real-time measurement of protein-induced conformational changes of DNA

A platform for in situ and real-time measurement of protein-induced conformational changes in dsDNA is presented. We combine electrical orientation of surface-bound dsDNA probes with an optical technique to measure the kinetics of DNA conformational changes. The sequence-specific Escherichia coli in...

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Detalhes bibliográficos
Main Authors: Spuhler, Philipp S., Knežević, Jelena, Yalçin, Ayça, Bao, Qiuye, Pringsheim, Erika, Dröge, Peter, Rant, Ulrich, Ünlü, M. Selim
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824355/
https://ncbi.nlm.nih.gov/pubmed/20080702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912182107
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