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Mechanistic details of a protein–protein association pathway revealed by paramagnetic relaxation enhancement titration measurements
Protein–protein association generally proceeds via the intermediary of a transient, lowly populated, encounter complex ensemble. The mechanism whereby the interacting molecules in this ensemble locate their final stereospecific structure is poorly understood. Further, a fundamental question is wheth...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824347/ https://ncbi.nlm.nih.gov/pubmed/20080627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909370107 |
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