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BRL 34915 (cromakalim) activates ATP-sensitive K+ current in cardiac muscle.

The mechanism by which the antihypertensive agent BRL 34915 (cromakalim) affects action potential duration (APD) and effective refractory period (ERP) in isolated cardiac muscle was investigated. BRL 34915 (greater than or equal to 3 microM) shortened ERP of ferret (Mustela putorius furo) and guinea...

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Main Authors: Sanguinetti, M C, Scott, A L, Zingaro, G J, Siegl, P K
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC282434/
https://ncbi.nlm.nih.gov/pubmed/2460868
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