Llwytho...

Rate, molecular spectrum, and consequences of human mutation

Although mutation provides the fuel for phenotypic evolution, it also imposes a substantial burden on fitness through the production of predominantly deleterious alleles, a matter of concern from a human-health perspective. Here, recently established databases on de novo mutations for monogenic diso...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Lynch, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824313/
https://ncbi.nlm.nih.gov/pubmed/20080596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912629107
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