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Mechanism of active targeting in solid tumors with transferrin-containing gold nanoparticles

PEGylated gold nanoparticles are decorated with various amounts of human transferrin (Tf) to give a series of Tf-targeted particles with near-constant size and electrokinetic potential. The effects of Tf content on nanoparticle tumor targeting were investigated in mice bearing s.c. Neuro2A tumors. Q...

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Autors principals: Choi, Chung Hang J., Alabi, Christopher A., Webster, Paul, Davis, Mark E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824286/
https://ncbi.nlm.nih.gov/pubmed/20080552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914140107
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