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Progressive Ankylosis Gene (ank) Regulates Osteoblast Differentiation

The progressive ankylosis gene (ank) is a transmembrane protein that transports intracellular pyrophosphate to the extracellular milieu. Human mutations of ank lead to craniometaphyseal dysplasia, a disease which is characterized by the overgrowth of craniofacial bones and osteopenia in long bones,...

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Autors principals: Kirsch, Thorsten, Kim, Hyon Jong, Winkles, Jeffrey A.
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824191/
https://ncbi.nlm.nih.gov/pubmed/18728347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000151725
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