Enhanced tonic GABA(A) inhibition in typical absence epilepsy

The cellular mechanisms underlying typical absence seizures, which characterize various idiopathic generalized epilepsies, are not fully understood, but impaired GABAergic inhibition remains an attractive hypothesis. In contrast, we show here that extrasynaptic GABA(A) receptor–dependent ‘tonic’ inh...

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Bibliographic Details
Main Authors: Cope, David W., Di Giovanni, Giuseppe, Fyson, Sarah J., Orbán, Gergely, Errington, Adam C., Lőrincz, Magor L., Gould, Timothy M., Carter, David A., Crunelli, Vincenzo
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824149/
https://ncbi.nlm.nih.gov/pubmed/19966779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2058
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