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Enhanced tonic GABA(A) inhibition in typical absence epilepsy

The cellular mechanisms underlying typical absence seizures, which characterize various idiopathic generalized epilepsies, are not fully understood, but impaired GABAergic inhibition remains an attractive hypothesis. In contrast, we show here that extrasynaptic GABA(A) receptor–dependent ‘tonic’ inh...

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Hlavní autoři: Cope, David W., Di Giovanni, Giuseppe, Fyson, Sarah J., Orbán, Gergely, Errington, Adam C., Lőrincz, Magor L., Gould, Timothy M., Carter, David A., Crunelli, Vincenzo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824149/
https://ncbi.nlm.nih.gov/pubmed/19966779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2058
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