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Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane
PURPOSE: Poly-(γ-l-glutamylglutamine)–paclitaxel (PGG–PTX) is a novel polymer-based formulation of paclitaxel (PTX) in which the PTX is linked to the polymer via ester bonds. PGG–PTX is of interest because it spontaneously forms very small nanoparticles in plasma. In mouse models, PGG–PTX increased...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824123/ https://ncbi.nlm.nih.gov/pubmed/19685054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1099-1 |
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