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In vitro assessment of cytochrome P450 inhibition and induction potential of azacitidine
PURPOSE: To assess the potential inhibitory and inductive effects of azacitidine on cytochrome P450 isozymes in vitro. METHODS: The inhibitory effects of azacitidine on various CYP isozymes were determined in human liver microsomes. In addition, the ability of azacitidine to induce CYP enzymes in cu...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Springer-Verlag
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824119/ https://ncbi.nlm.nih.gov/pubmed/20119716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1245-9 |
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