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Spontaneous M6 protein size mutants of group A streptococci display variation in antigenic and opsonogenic epitopes.

Deletions of highly, but not entirely, homologous intragenic sequence repeats result in amino acid sequence and conformational changes in the M proteins of spontaneous M protein-size variants of group A streptococci. To determine if antigenic changes occurred as a result of these deletion mutations,...

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Bibliographic Details
Main Authors: Jones, K F, Hollingshead, S K, Scott, J R, Fischetti, V A
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC282411/
https://ncbi.nlm.nih.gov/pubmed/2460864
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