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Spontaneous M6 protein size mutants of group A streptococci display variation in antigenic and opsonogenic epitopes.

Deletions of highly, but not entirely, homologous intragenic sequence repeats result in amino acid sequence and conformational changes in the M proteins of spontaneous M protein-size variants of group A streptococci. To determine if antigenic changes occurred as a result of these deletion mutations,...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Jones, K F, Hollingshead, S K, Scott, J R, Fischetti, V A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282411/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2460864/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.8271
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