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Mapping of the gene encoding the beta-amyloid precursor protein and its relationship to the Down syndrome region of chromosome 21.

The gene encoding the beta-amyloid precursor protein has been assigned to human chromosome 21, as has a gene responsible for at least some cases of familial Alzheimer disease. Linkage studies strongly suggest that the beta-amyloid precursor protein and the product corresponding to familial Alzheimer...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Patterson, D, Gardiner, K, Kao, F T, Tanzi, R, Watkins, P, Gusella, J F
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282410/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2973063/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.8266
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