Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas

The basic helix-loop-helix transcription factor Neurog3 (Neurogenin3 or Ngn3) actively drives endodermal progenitor cells towards endocrine islet cell differentiation during embryogenesis. Here, we manipulate Neurog3 expression levels in endocrine progenitor cells without altering its expression pat...

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Bibliografiske detaljer
Main Authors: Wang, Sui, Yan, Jingbo, Anderson, Daniel A., Xu, Yanwen, Kanal, Maneesh C., Cao, Zheng, Wright, Christopher V. E., Gu, Guoqiang
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824035/
https://ncbi.nlm.nih.gov/pubmed/20025861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.12.009
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