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Hypoxia and the expression of HIF-1α and HIF-2α in the retina of streptozotocin-injected mice and rats
Decreases in retinal blood flow in diabetics could render the retina hypoxic. In mouse and rat models of diabetes, a decrease in retinal blood flow occurs early, within 3–4 weeks of the induction of hyperglycemia, although information is scarce on whether this early decrease in flow induces hypoxia....
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824016/ https://ncbi.nlm.nih.gov/pubmed/20005221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2009.12.002 |
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